Global Calcium is one of the leading manufacturers and exporters of
Aprepitant CAS no. 170729-80-3, API, (Active Pharmaceutical Ingredient). We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.
As manufacturer of Aprepitant we hereby state the following facts about the drug:
Indications for Use
Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy.
Mechanism of Action
Aprepitant inhibits emesis induced by cytotoxic chemotherapeutic agents, such as cisplatin, via central actions.
Aprepitant crosses the blood brain barrier and occupies brain NK1 receptors. It also augments the antiemetic activity of the 5-HT3-receptor antagonist ondansetron and the corticosteroid ethasone and inhibits both the acute and delayed phases of cisplatin induced emesis.
Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market