Calcium Di Sodium Versenate (Edetate Calcium Disodium)

Global Calcium is one of the leading manufacturers and exporters of Calcium Di Sodium Versenate (Edetate Calcium Disodium) CAS no. 62-33-9, Mineral Actives . We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.

As manufacturer of Calcium Di Sodium Versenate (Edetate Calcium Disodium) we hereby state the following facts about the drug:

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines.

Drug indication:

Edetate calcium disodium is indicated to reduce blood levels and depot stores of lead in acute and chronic lead poisoning.

Pharmacology:

Edetate calcium disodium is a polyvalent ion chelator used to remove lead from the body after lead poisoning. It has a wide therapeutic index, as overdoses must be well in excess of the therapeutic dose to show symptoms. It has a long duration of action, as doses are given at least a day apart. Patients should be counseled regarding the risk of increased intracranial pressure with intravenous infusions.

Mechanism of action:

Edetate calcium disodium distributes into tissues, such as the kidney and bone, where it chelates lead ions. The lead ions are then eliminated in the normal urinary excretion of edetate. Lead in certain tissues such as the liver and bone, redistribute to other tissues after edetate calcium disodium treatment, but lead levels do not decrease to levels seen in unexposed patients.

Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market