Global Calcium is one of the leading manufacturers and exporters of
Calcium Sulfate CAS no. 7778-18-9, Mineral Actives
. We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.
As manufacturer of Calcium Sulfate we hereby state the following facts about the drug:
Calcium sulfate was first used in 1892 in Germany. Dreesman (1892) used calcium sulfate to fill bone defects in eight patients. Six of these patients presented with tuberculous cavities. Three of these six patients showed extensive bone formation and two of them showed no signs of healing. One patient had two cavities, of which one healed very well while the other one did not. Out of the remaining two patients, one patient had an enchondroma of the fifth metacarpal and the other one had a bone cavity due to osteomyelitis. In the case of the patient with the enchondroma, the tumor was excised and the resulting cavity was filled with calcium sulfate pellets. This cavity showed significant bone growth. The osteomyelitis cavity also healed well. Overall, calcium sulfate worked very well as a bone graft material. Although sporadic reports of calcium sulfate use in bone repair appeared in the literature, the material was not widely used. Ljubovic and Nikulin (1956) published a detailed report about how calcium sulfate works in vivo in rabbits.
He also concluded that calcium sulfate acted mainly as a space filler and its most important property was its rate of degradation in the body. He also concluded that its rate of degradation coincided with the rate at which natural bone can grow into a defect.
Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market