Zinc Sulphate USP
- Product Name : Zinc Sulphate
- CAS : 7733-02-0
- Molecular Formula : ZnSO4
- Molecular Weight : 161.4 g/mol
- Pharmaceutical Grade : USP
- Therapeutic Category : Dietary Supplement
Global Calcium is one of the leading manufacturers and exporters of Zinc Sulphate CAS no. 7733-02-0, Mineral Actives . We support the customers with exhaustive documentation. As a USDMF & EU-GMP certified global company and an established hallmark for pharmaceutical standards, Global Calcium has stood the test of time since its inception in 1979.
As manufacturer of Zinc Sulphate we hereby state the following facts about the drug:
Zinc sulfate is a drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency. Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is a metal sulfate and a zinc molecular entity. It contains a zinc(2+). Zinc sulfate is soluble in water and noncombustible. It has a role as a fertilizer. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Drug indication:
This medication is a mineral used to treat or prevent low levels of zinc alone and together with oral rehydration therapy (ORT). It is also used as a topical astringent. Zinc Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for TPN.
Pharmacology:
Zinc has been identified as a cofactor for over 70 different enzymes, including alkaline phosphatase, lactic dehydrogenase and both RNA and DNA polymerase. Zinc facilitates wound healing, helps maintain normal growth rates, normal skin hydration and the senses of taste and smell.
Pharmacodynamics:
Zinc has been identified as a cofactor for over 70 different enzymes, including alkaline phosphatase, lactic dehydrogenase and both RNA and DNA polymerase. Zinc facilitates wound healing, helps maintain normal growth rates, normal skin hydration and the senses of taste and smell.
Mechanism of action:
Zinc inhibits cAMP-induced, chloride-dependent fluid secretion by inhibiting basolateral potassium (K) channels, in in-vitro studies with rat ileum. This study has also shown the specificity of Zn to cAMP-activated K channels, because zinc did not block the calcium (Ca)-mediated K channels. As this study was not performed in Zn-deficient animals, it provides evidence that Zn is probably effective in the absence of Zn deficiency. Zinc also improves the absorption of water and electrolytes, improves regeneration of the intestinal epithelium, increases the levels of brush border enzymes, and enhances the immune response, allowing for a better clearance of the pathogens.
In a study, Topical zinc sulfate solution used three times daily for 4 weeks led to a higher cure rate than water placebo in a double-blind trial of 40 patients with plane warts and 50 patients with common warts. The cure rate appeared to be dependent on the concentration of zinc solution used and was better for plane than common warts.
Global Calcium is a leading manufacturer of this drug. We manufacture this pharmaceutical drug and make it available to domestic and overseas market